Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | BIOCARTA_KERATINOCYTE DIFFERENTIATION |
| Enrichment Score (ES) | -0.6532357 |
| Normalized Enrichment Score (NES) | -1.6183285 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.16388279 |
| FWER p-Value | 0.755 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HRAS | 1980551 | 798 | 3.458 | 0.0039 | No | ||
| 2 | GRB2 | 6650398 | 1856 | 1.865 | -0.0277 | No | ||
| 3 | MAPK3 | 580161 4780035 | 2169 | 1.520 | -0.0239 | No | ||
| 4 | MAPK13 | 6760215 | 2554 | 1.165 | -0.0288 | No | ||
| 5 | ETS1 | 5270278 6450717 6620465 | 3049 | 0.850 | -0.0439 | No | ||
| 6 | MAP2K2 | 4590601 | 3323 | 0.686 | -0.0493 | No | ||
| 7 | FAS | 4480112 6110040 | 3371 | 0.658 | -0.0429 | No | ||
| 8 | PRKCA | 6400551 | 3491 | 0.607 | -0.0410 | No | ||
| 9 | CEBPA | 5690519 | 5297 | 0.204 | -0.1355 | No | ||
| 10 | EGFR | 4920138 6480521 | 5664 | 0.167 | -0.1529 | No | ||
| 11 | PPP2R5D | 4010156 380408 5550112 5670162 | 6069 | 0.132 | -0.1729 | No | ||
| 12 | MAP2K7 | 2260086 | 6441 | 0.111 | -0.1914 | No | ||
| 13 | PLAT | 6860128 | 6453 | 0.110 | -0.1905 | No | ||
| 14 | RIPK1 | 3190025 | 6652 | 0.100 | -0.1998 | No | ||
| 15 | PRKCH | 5720079 | 7131 | 0.080 | -0.2244 | No | ||
| 16 | FOS | 1850315 | 7375 | 0.071 | -0.2366 | No | ||
| 17 | SOS1 | 7050338 | 7718 | 0.062 | -0.2541 | No | ||
| 18 | PRKCE | 5700053 | 10501 | 0.007 | -0.4039 | No | ||
| 19 | PRKCQ | 2260170 3870193 | 11611 | -0.012 | -0.4635 | No | ||
| 20 | MAP2K3 | 5570193 | 11952 | -0.019 | -0.4815 | No | ||
| 21 | TNF | 6650603 | 12392 | -0.029 | -0.5048 | No | ||
| 22 | MAP3K5 | 6020041 6380162 | 12791 | -0.040 | -0.5256 | No | ||
| 23 | JUN | 840170 | 13860 | -0.095 | -0.5819 | No | ||
| 24 | EGF | 5220154 | 14409 | -0.162 | -0.6092 | No | ||
| 25 | PRKCD | 770592 | 14588 | -0.197 | -0.6161 | No | ||
| 26 | BIRC3 | 6550411 | 14862 | -0.275 | -0.6271 | No | ||
| 27 | FASLG | 2810044 | 15236 | -0.397 | -0.6418 | No | ||
| 28 | SHC1 | 2900731 3170504 6520537 | 15383 | -0.470 | -0.6433 | Yes | ||
| 29 | IKBKG | 3450092 3840377 6590592 | 15489 | -0.523 | -0.6418 | Yes | ||
| 30 | BIRC2 | 2940435 4730020 | 15520 | -0.538 | -0.6362 | Yes | ||
| 31 | MAP2K1 | 840739 | 15572 | -0.564 | -0.6313 | Yes | ||
| 32 | MAPK1 | 3190193 6200253 | 15779 | -0.675 | -0.6332 | Yes | ||
| 33 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16152 | -0.932 | -0.6406 | Yes | ||
| 34 | MAP2K4 | 5130133 | 16267 | -0.996 | -0.6332 | Yes | ||
| 35 | DAXX | 4010647 | 16526 | -1.210 | -0.6307 | Yes | ||
| 36 | MAPK8 | 2640195 | 16851 | -1.569 | -0.6269 | Yes | ||
| 37 | IKBKB | 6840072 | 16924 | -1.659 | -0.6083 | Yes | ||
| 38 | MAP4K4 | 2360059 | 17084 | -1.820 | -0.5921 | Yes | ||
| 39 | CHUK | 7050736 | 17108 | -1.856 | -0.5682 | Yes | ||
| 40 | SP1 | 6590017 | 17158 | -1.914 | -0.5449 | Yes | ||
| 41 | RELA | 3830075 | 17212 | -1.973 | -0.5210 | Yes | ||
| 42 | RAF1 | 1770600 | 17308 | -2.124 | -0.4973 | Yes | ||
| 43 | MAPK14 | 5290731 | 17669 | -2.766 | -0.4791 | Yes | ||
| 44 | MAP3K1 | 5360347 | 17735 | -2.897 | -0.4433 | Yes | ||
| 45 | MAP2K6 | 1230056 2940204 | 17853 | -3.155 | -0.4068 | Yes | ||
| 46 | NFKBIA | 1570152 | 17856 | -3.162 | -0.3641 | Yes | ||
| 47 | HOXA7 | 5910152 | 17999 | -3.526 | -0.3239 | Yes | ||
| 48 | TRAF2 | 5900148 | 18197 | -4.188 | -0.2777 | Yes | ||
| 49 | TRAF1 | 3440735 | 18269 | -4.576 | -0.2194 | Yes | ||
| 50 | ETS2 | 360451 | 18601 | -8.428 | -0.1229 | Yes | ||
| 51 | TNFRSF1A | 1090390 6520735 | 18612 | -9.119 | 0.0002 | Yes |
